BDBM142536 US8933224, 129
SMILES: CCn1c(C)nc2CCN(Cc2c1=O)c1ncnn2c(C)nc([C@@H]3CCOC3)c12
InChI Key: InChIKey=OBRNLARPNKFQOP-CQSZACIVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat)) | BDBM142536 (US8933224, 129) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0998 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Pfizer Inc. US Patent | Assay Description The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ... | US Patent US8933224 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C35 | |||||||||||
More data for this Ligand-Target Pair |