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BDBM142607 US8933228, 14

SMILES: COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ncccc12)C(C)(C)C

InChI Key: InChIKey=QGFOJZMDPXDGSA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142607   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM142607
PNG
(US8933228, 14)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ncccc12)C(C)(C)C
Show InChI InChI=1S/C30H28N8O4/c1-30(2,3)23-16-24(38(37-23)17-7-9-18(41-4)10-8-17)34-28(39)33-20-11-12-21(25-19(20)6-5-14-31-25)42-22-13-15-32-27-26(22)35-29(40)36-27/h5-16H,1-4H3,(H2,33,34,39)(H2,32,35,36,40)
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PC cid
PC sid
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US Patent
n/an/a 5n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM142607
PNG
(US8933228, 14)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ncccc12)C(C)(C)C
Show InChI InChI=1S/C30H28N8O4/c1-30(2,3)23-16-24(38(37-23)17-7-9-18(41-4)10-8-17)34-28(39)33-20-11-12-21(25-19(20)6-5-14-31-25)42-22-13-15-32-27-26(22)35-29(40)36-27/h5-16H,1-4H3,(H2,33,34,39)(H2,32,35,36,40)
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UniChem
US Patent
n/an/a 0.800n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM142607
PNG
(US8933228, 14)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ncccc12)C(C)(C)C
Show InChI InChI=1S/C30H28N8O4/c1-30(2,3)23-16-24(38(37-23)17-7-9-18(41-4)10-8-17)34-28(39)33-20-11-12-21(25-19(20)6-5-14-31-25)42-22-13-15-32-27-26(22)35-29(40)36-27/h5-16H,1-4H3,(H2,33,34,39)(H2,32,35,36,40)
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n/an/a<2n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair
p38 delta/gamma


(Homo sapiens (Human))
BDBM142607
PNG
(US8933228, 14)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ncccc12)C(C)(C)C
Show InChI InChI=1S/C30H28N8O4/c1-30(2,3)23-16-24(38(37-23)17-7-9-18(41-4)10-8-17)34-28(39)33-20-11-12-21(25-19(20)6-5-14-31-25)42-22-13-15-32-27-26(22)35-29(40)36-27/h5-16H,1-4H3,(H2,33,34,39)(H2,32,35,36,40)
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UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 180n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair