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BDBM142629 US8933228, 21

SMILES: Cc1ccc(s1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)c2ccccc12)C(C)(C)C

InChI Key: InChIKey=KIPZYDCBLYBUMY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142629   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM142629
PNG
(US8933228, 21)
Show SMILES Cc1ccc(s1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C30H27N7O3S/c1-17-9-12-26(41-17)37-24(15-23(36-37)30(2,3)4)34-29(39)33-20-10-11-21(19-8-6-5-7-18(19)20)40-22-13-14-31-28-27(22)32-16-25(38)35-28/h5-16H,1-4H3,(H,31,35,38)(H2,33,34,39)
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PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



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US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM142629
PNG
(US8933228, 21)
Show SMILES Cc1ccc(s1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C30H27N7O3S/c1-17-9-12-26(41-17)37-24(15-23(36-37)30(2,3)4)34-29(39)33-20-10-11-21(19-8-6-5-7-18(19)20)40-22-13-14-31-28-27(22)32-16-25(38)35-28/h5-16H,1-4H3,(H,31,35,38)(H2,33,34,39)
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US Patent
n/an/a 17n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM142629
PNG
(US8933228, 21)
Show SMILES Cc1ccc(s1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C30H27N7O3S/c1-17-9-12-26(41-17)37-24(15-23(36-37)30(2,3)4)34-29(39)33-20-10-11-21(19-8-6-5-7-18(19)20)40-22-13-14-31-28-27(22)32-16-25(38)35-28/h5-16H,1-4H3,(H,31,35,38)(H2,33,34,39)
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n/an/a 3n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair
p38 delta/gamma


(Homo sapiens (Human))
BDBM142629
PNG
(US8933228, 21)
Show SMILES Cc1ccc(s1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C30H27N7O3S/c1-17-9-12-26(41-17)37-24(15-23(36-37)30(2,3)4)34-29(39)33-20-10-11-21(19-8-6-5-7-18(19)20)40-22-13-14-31-28-27(22)32-16-25(38)35-28/h5-16H,1-4H3,(H,31,35,38)(H2,33,34,39)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 41n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...


US Patent US8933228 (2015)


BindingDB Entry DOI: 10.7270/Q2RV0MDW
More data for this
Ligand-Target Pair