BDBM142702 US8937084, 4
SMILES: NC(=O)CN1C[C@H]2[C@H]3Cc4ccc(O)cc4[C@@]2(CCN3CC2CC2)CC1=O
InChI Key: InChIKey=LYLWKMFSKRHION-WAOWUJCRSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM142702 (US8937084, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.550 | -13.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM142702 (US8937084, 4) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 24.4 | -11.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM142702 (US8937084, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 49.0 | -10.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C | |||||||||||
More data for this Ligand-Target Pair |