BDBM142705 US8937084, 7

SMILES: Oc1ccc2C[C@@H]3[C@@H]4CNC(=O)C[C@]4(CCN3CC3CC3)c2c1

InChI Key: InChIKey=XYEIPZFSMVUKKD-YQVWRLOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 142705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM142705 (US8937084, 7) Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CNC(=O)C[C@]4(CCN3CC3CC3)c2c1 |r| Show InChI InChI=1S/C19H24N2O2/c22-14-4-3-13-7-17-16-10-20-18(23)9-19(16,15(13)8-14)5-6-21(17)11-12-1-2-12/h3-4,8,12,16-17,22H,1-2,5-7,9-11H2,(H,20,23)/t16-,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.180	-14.4	n/a	n/a	n/a	n/a	n/a	7.4	50
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...				US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM142705 (US8937084, 7) Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CNC(=O)C[C@]4(CCN3CC3CC3)c2c1 |r| Show InChI InChI=1S/C19H24N2O2/c22-14-4-3-13-7-17-16-10-20-18(23)9-19(16,15(13)8-14)5-6-21(17)11-12-1-2-12/h3-4,8,12,16-17,22H,1-2,5-7,9-11H2,(H,20,23)/t16-,17+,19+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.61	-12.2	n/a	n/a	n/a	n/a	n/a	7.4	50
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...				US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM142705 (US8937084, 7) Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CNC(=O)C[C@]4(CCN3CC3CC3)c2c1 |r| Show InChI InChI=1S/C19H24N2O2/c22-14-4-3-13-7-17-16-10-20-18(23)9-19(16,15(13)8-14)5-6-21(17)11-12-1-2-12/h3-4,8,12,16-17,22H,1-2,5-7,9-11H2,(H,20,23)/t16-,17+,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	15.0	-11.6	n/a	n/a	n/a	n/a	n/a	7.4	50
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...				US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C
					More data for this Ligand-Target Pair