BDBM142712 US8937084, 14

SMILES: C[C@H](N)C(=O)N1CC[C@]23CCN(CC4CC4)[C@H](Cc4ccc(O)cc24)[C@@H]3C1

InChI Key: InChIKey=BOWGWIMAPHYDBF-SKWWBAPZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM142712 (US8937084, 14) Show SMILES C[C@H](N)C(=O)N1CC[C@]23CCN(CC4CC4)[C@H](Cc4ccc(O)cc24)[C@@H]3C1 |r| Show InChI InChI=1S/C22H31N3O2/c1-14(23)21(27)25-9-7-22-6-8-24(12-15-2-3-15)20(19(22)13-25)10-16-4-5-17(26)11-18(16)22/h4-5,11,14-15,19-20,26H,2-3,6-10,12-13,23H2,1H3/t14-,19-,20+,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0900	-14.8	n/a	n/a	n/a	n/a	n/a	7.4	50
Purdue Pharma L.P. US Patent					Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane...				US Patent US8937084 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C5C
					More data for this Ligand-Target Pair