BDBM142818 US8940736, 313
SMILES: FC1CN(CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1Cl)C#N)C1COC1
InChI Key: InChIKey=QZXOHCNHILBVDI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha' (Homo sapiens (Human)) | BDBM142818 (US8940736, 313) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Bristol-Myers Squibb Company US Patent | Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th... | US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM142818 (US8940736, 313) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Bristol-Myers Squibb Company US Patent | Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th... | US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72 | |||||||||||
More data for this Ligand-Target Pair |