BDBM143534 US9682955, 81

SMILES: CCOC(=O)CCC(=O)N1CCC(CC1)Nc1ncnc2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=XVGMPCNNHOZVDP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM143534 (US9682955, 81) Show SMILES CCOC(=O)CCC(=O)N1CCC(CC1)Nc1ncnc2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C32H32Cl2N4O3/c1-2-41-30(40)14-13-29(39)38-17-15-26(16-18-38)37-32-27-19-23(7-12-28(27)35-20-36-32)31(21-3-8-24(33)9-4-21)22-5-10-25(34)11-6-22/h3-12,19-20,26,31H,2,13-18H2,1H3,(H,35,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	452	n/a	n/a	n/a	27
Janssen Pharmaceutica NV US Patent					Assay Description The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...				US Patent US9682955 (2017) BindingDB Entry DOI: 10.7270/Q2707ZM3
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM143534 (US9682955, 81) Show SMILES CCOC(=O)CCC(=O)N1CCC(CC1)Nc1ncnc2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C32H32Cl2N4O3/c1-2-41-30(40)14-13-29(39)38-17-15-26(16-18-38)37-32-27-19-23(7-12-28(27)35-20-36-32)31(21-3-8-24(33)9-4-21)22-5-10-25(34)11-6-22/h3-12,19-20,26,31H,2,13-18H2,1H3,(H,35,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	27
Janssen Pharmaceutica NV US Patent					Assay Description The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...				US Patent US9682955 (2017) BindingDB Entry DOI: 10.7270/Q2707ZM3
					More data for this Ligand-Target Pair