BDBM144271 US8952008, 39

SMILES: CCS(=O)(=O)c1ccc(c(Cl)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C

InChI Key: InChIKey=AUSBOPQXKDERQI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144271   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA A receptor alpha-2/beta-2/gamma-2 (Homo sapiens (Human))	BDBM144271 (US8952008, 39) Show SMILES CCS(=O)(=O)c1ccc(c(Cl)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C Show InChI InChI=1S/C22H20ClFN4O2S/c1-4-31(29,30)15-6-7-16(19(23)10-15)17-9-14(5-8-20(17)24)18-11-26-27-22-21(18)25-12-28(22)13(2)3/h5-13H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
					More data for this Ligand-Target Pair