BDBM144277 US8969333, YW3-56
SMILES: CN(C)c1ccc2cc(ccc2c1)C(=O)N[C@@H](CCCNC(=N)CCl)C(=O)NCc1ccccc1
InChI Key: InChIKey=LJJCYRVBDASIDX-DEOSSOPVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peptidylarginine deiminase 4 (PAD4) (Homo sapiens (Human)) | BDBM144277 (US8969333, YW3-56) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
The Penn State Research Foundation US Patent | Assay Description The inhibition efficacy of PAD4 inhibitors were determined by colorimetric measurement of citrulline generated by PAD4 catalyzed citrullination of BA... | US Patent US8969333 (2015) BindingDB Entry DOI: 10.7270/Q2SN07P5 | |||||||||||
More data for this Ligand-Target Pair |