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BDBM144503 US8969568, 56

SMILES: CCOc1cc(cc(OCC)c1OCC)-c1cc2ncccc2c(O[C@H](C)[C@H]2CNC(=O)C2)n1

InChI Key: InChIKey=XIRFKMIHHAWLMI-AWMLGPFDNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144503   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM144503
PNG
(US8969568, 56)
Show SMILES CCOc1cc(cc(OCC)c1OCC)-c1cc2ncccc2c(O[C@H](C)[C@H]2CNC(=O)C2)n1 |r|
Show InChI InChI=1/C26H31N3O5/c1-5-31-22-11-17(12-23(32-6-2)25(22)33-7-3)20-14-21-19(9-8-10-27-21)26(29-20)34-16(4)18-13-24(30)28-15-18/h8-12,14,16,18H,5-7,13,15H2,1-4H3,(H,28,30)/t16-,18-/s2
PDB
MMDB

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KEGG

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.700n/an/an/an/an/an/a



Boehringer Ingelheim Pharma GmbH & Co. KG

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US8969568 (2015)


BindingDB Entry DOI: 10.7270/Q2154FRD
More data for this
Ligand-Target Pair