BDBM14671 Fragment 1::Phosphate::phosphoric acid
SMILES: OP(O)(O)=O
InChI Key: InChIKey=NBIIXXVUZAFLBC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ornithine carbamoyltransferase (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine carbamoyltransferase (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.20E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM Tris.HCl, 0.5 ... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ornithine carbamoyltransferase (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
Universit£tstrasse 16 Curated by ChEMBL | Assay Description Binding affinity against ornithine transcarbamoylase (OTC) produced by Streptococcus faecalis The buffer taken for this study is 50 mM maleate, 0.5 m... | J Med Chem 42: 2633-40 (1999) Article DOI: 10.1021/jm991008q BindingDB Entry DOI: 10.7270/Q2NV9JX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ketopantoate reductase (Escherichia coli (strain K12)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.70E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Chemical Laboratory Curated by ChEMBL | Assay Description Inhibition of Escherichia coli KPR | J Med Chem 49: 4992-5000 (2006) Article DOI: 10.1021/jm060490r BindingDB Entry DOI: 10.7270/Q28S4QQN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (aa 145-252) (Homo sapiens (Human)) | BDBM14671 (Fragment 1 | Phosphate | phosphoric acid) | PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | >4.00E+7 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Aventis Pharma | Assay Description SPA uses 125I as energy donor and scintillant-coated beads as energy acceptor. The labeled ligand is captured by the biotinylated Src-SH2 protein imm... | J Med Chem 46: 5184-95 (2003) Article DOI: 10.1021/jm020970s BindingDB Entry DOI: 10.7270/Q2XW4H14 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |