Found 6 hits for monomerid = 14675 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Proto-oncogene tyrosine-protein kinase Src (aa 145-252)
(Homo sapiens (Human)) | BDBM14675
(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) | PDB MMDB
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB Article PubMed
| n/a | n/a | 3.50E+6 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Aventis Pharma
| Assay Description SPA uses 125I as energy donor and scintillant-coated beads as energy acceptor. The labeled ligand is captured by the biotinylated Src-SH2 protein imm... |
J Med Chem 46: 5184-95 (2003)
Article DOI: 10.1021/jm020970s BindingDB Entry DOI: 10.7270/Q2XW4H14 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM14675
(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis
Curated by ChEMBL
| Assay Description Binding affinity for Src protein tryrosine kinase SH2 domain using surface plasmon resonance (SPR) assay |
J Med Chem 45: 2379-87 (2002)
BindingDB Entry DOI: 10.7270/Q21J992G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Serum paraoxonase/arylesterase 1
(Homo sapiens (Human)) | BDBM14675
(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.25E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham
Curated by ChEMBL
| Assay Description Inhibitory activity against human serum paraoxonase (PON1) |
Bioorg Med Chem Lett 13: 1623-6 (2003)
BindingDB Entry DOI: 10.7270/Q23B60P7 |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM14675
(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis
Curated by ChEMBL
| Assay Description Binding affinity for Src protein tryrosine kinase SH2 domainusing scintillation proximity binding assay (SPA) |
J Med Chem 45: 2379-87 (2002)
BindingDB Entry DOI: 10.7270/Q21J992G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM14675
(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 2.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharma
Curated by ChEMBL
| Assay Description The compound was evaluated for its binding affinity towards phosphotyrosine binding pocket of Src protein tryrosine kinase SH2 domain |
Bioorg Med Chem Lett 12: 1295-8 (2002)
BindingDB Entry DOI: 10.7270/Q2959GW0 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM14675
(CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...)Show InChI InChI=1S/C6H7O4P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H,(H2,7,8,9) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against Lck SH2 domain |
Bioorg Med Chem Lett 9: 2403-6 (1999)
BindingDB Entry DOI: 10.7270/Q2Z89BK7 |
More data for this Ligand-Target Pair | |