BDBM147346 US8957093, 180

SMILES: Cc1c(C)c2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1)C(=O)NC(C)(C)c1ccc(Br)cc1

InChI Key: InChIKey=UQVXHOYYFWSPPJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM147346 (US8957093, 180) Show SMILES Cc1c(C)c2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1)C(=O)NC(C)(C)c1ccc(Br)cc1 Show InChI InChI=1S/C33H31BrN2O/c1-22-23(2)36(21-24-10-12-26(13-11-24)25-8-6-5-7-9-25)31-19-14-27(20-30(22)31)32(37)35-33(3,4)28-15-17-29(34)18-16-28/h5-20H,21H2,1-4H3,(H,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute US Patent					Assay Description The assay was performed according to manufacturer protocol. A mixture of nM GST-PPARG-LBD, 5 nM Tb-GST-antibody, 5 nM Fluormone Pan-PPAR Green, and s...				US Patent US8957093 (2015) BindingDB Entry DOI: 10.7270/Q2X63KNR
					More data for this Ligand-Target Pair