BDBM148153 US8962612, 8
SMILES: [#7]\[#6](-[#7])=[#7]\[#6](=O)-[#7]-1-[#6]-[#6]-c2cccc(c2-[#6]-1)-c1cc(F)c(F)cc1F
InChI Key: InChIKey=RDEDININJACLDX-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148153 (US8962612, 8) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.60 | -12.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair |