BDBM148160 US8962612, 60
SMILES: [#6]-c1ccc(c2-[#6]-[#7](-[#6]-[#6]-c12)-[#6](=O)\[#7]=[#6](\[#7])-[#7])-c1ncc(F)cc1F
InChI Key: InChIKey=CLTGYVRNFWMWCO-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM148160 (US8962612, 60) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.90 | -11.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Astellas Pharma Inc. US Patent | Assay Description A test compound and 150 uM of a DMSO solution of 5-carboxamide tryptamine (5-CT) were added to a 96-well plate at 2 ul/well and suspended in the incu... | US Patent US8962612 (2015) BindingDB Entry DOI: 10.7270/Q24Q7SQP | |||||||||||
More data for this Ligand-Target Pair |