BDBM148992 US8962648, 65

SMILES: NS(=O)(=O)c1ccc(cc1)-c1c(O)ccc2[nH]c(=O)c3sccc3c12

InChI Key: InChIKey=SKFYJZPHCZZCCE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 148992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDZ-binding kinase (Homo sapiens (Human))	BDBM148992 (US8962648, 65) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1c(O)ccc2[nH]c(=O)c3sccc3c12 Show InChI InChI=1S/C17H12N2O4S2/c18-25(22,23)10-3-1-9(2-4-10)14-13(20)6-5-12-15(14)11-7-8-24-16(11)17(21)19-12/h1-8,20H,(H,19,21)(H2,18,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.4	25
OncoTherapy Science, Inc. US Patent					Assay Description PBK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a s...				US Patent US8962648 (2015) BindingDB Entry DOI: 10.7270/Q27H1H9K
					More data for this Ligand-Target Pair