BDBM149034 US8962648, 266

SMILES: NCc1ccc(s1)-c1c(O)ccc2[nH]c(=O)c3sccc3c12

InChI Key: InChIKey=YJLUSYSZDWUAAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDZ-binding kinase (Homo sapiens (Human))	BDBM149034 (US8962648, 266) Show SMILES NCc1ccc(s1)-c1c(O)ccc2[nH]c(=O)c3sccc3c12 Show InChI InChI=1S/C16H12N2O2S2/c17-7-8-1-4-12(22-8)14-11(19)3-2-10-13(14)9-5-6-21-15(9)16(20)18-10/h1-6,19H,7,17H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.780	n/a	n/a	n/a	n/a	7.4	25
OncoTherapy Science, Inc. US Patent					Assay Description PBK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a s...				US Patent US8962648 (2015) BindingDB Entry DOI: 10.7270/Q27H1H9K
					More data for this Ligand-Target Pair