BDBM149044 US8962648, 278
SMILES: OC1CCN(Cc2ccc(cc2F)-c2c(O)ccc3[nH]c(=O)c4sccc4c23)C1
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDZ-binding kinase (Homo sapiens (Human)) | BDBM149044 (US8962648, 278) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.970 | n/a | n/a | n/a | n/a | 7.4 | 25 |
OncoTherapy Science, Inc. US Patent | Assay Description PBK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a s... | US Patent US8962648 (2015) BindingDB Entry DOI: 10.7270/Q27H1H9K | |||||||||||
More data for this Ligand-Target Pair |