BDBM149056 US8962648, 327

SMILES: CN(C)CCc1ccc(cc1F)-c1c(O)ccc2[nH]c(=O)c3sccc3c12

InChI Key: InChIKey=QTBDIELUWFNQIF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDZ-binding kinase (Homo sapiens (Human))	BDBM149056 (US8962648, 327) Show SMILES CN(C)CCc1ccc(cc1F)-c1c(O)ccc2[nH]c(=O)c3sccc3c12 Show InChI InChI=1S/C21H19FN2O2S/c1-24(2)9-7-12-3-4-13(11-15(12)22)18-17(25)6-5-16-19(18)14-8-10-27-20(14)21(26)23-16/h3-6,8,10-11,25H,7,9H2,1-2H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.4	25
OncoTherapy Science, Inc. US Patent					Assay Description PBK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a s...				US Patent US8962648 (2015) BindingDB Entry DOI: 10.7270/Q27H1H9K
					More data for this Ligand-Target Pair