BDBM149225 US8962651, 9
SMILES: CNC(=O)c1c(oc2nc(CCC(F)(F)F)c(cc12)-c1cccc(c1)C(=O)NC(C)(C)c1nc(C)no1)-c1ccc(F)cc1
InChI Key: InChIKey=LAHKQDLBUJOYNF-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RNA polymerase (NS5B) (Hepatitis C virus (HCV)) | BDBM149225 (US8962651, 9) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.87 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description An on-bead solid phase homogeneous assay was used in a 384-well format to assess NS5B inhibitors (WangY-K, Rigat K, Roberts S, and Gao M (2006) Anal ... | US Patent US8962651 (2015) BindingDB Entry DOI: 10.7270/Q23R0RM9 | |||||||||||
More data for this Ligand-Target Pair |