BDBM149234 US8962674, CU085

SMILES: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2OC)ccc1O

InChI Key: InChIKey=QAOTWNNTGAUPFL-IUMFQGNOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM149234 (US8962674, CU085) Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2OC)ccc1O Show InChI InChI=1S/C21H20O6/c1-26-20-13-18(24)9-6-15(20)5-8-17(23)12-16(22)7-3-14-4-10-19(25)21(11-14)27-2/h3-11,13,24-25H,12H2,1-2H3/b7-3+,8-5+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Doshisha University Curated by ChEMBL					Assay Description Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...				Bioorg Med Chem Lett 26: 5024-5028 (2016) Article DOI: 10.1016/j.bmcl.2016.08.092 BindingDB Entry DOI: 10.7270/Q2833V0M
					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM149234 (US8962674, CU085) Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2OC)ccc1O Show InChI InChI=1S/C21H20O6/c1-26-20-13-18(24)9-6-15(20)5-8-17(23)12-16(22)7-3-14-4-10-19(25)21(11-14)27-2/h3-11,13,24-25H,12H2,1-2H3/b7-3+,8-5+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	4.5	37
Tokyo Institute of Technology; Kyoto University US Patent					Assay Description Compounds were dissolved in dimethylsulfoxide (DMSO), and further diluted in 0.1 M sodium acetate buffer (with 150 mM sodium chloride, pH 4.5). The s...				US Patent US8962674 (2015) BindingDB Entry DOI: 10.7270/Q2QJ7G1J
					More data for this Ligand-Target Pair