BDBM150831 US8981106, 20

SMILES: CC1(C)OB(OC1(C)C)c1ccc(CSc2ccc(cn2)C(=O)Nc2ccc(F)cc2)cc1

InChI Key: InChIKey=JWLGJWBCFUDHLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM150831 (US8981106, 20) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(CSc2ccc(cn2)C(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H26BFN2O3S/c1-24(2)25(3,4)32-26(31-24)19-8-5-17(6-9-19)16-33-22-14-7-18(15-28-22)23(30)29-21-12-10-20(27)11-13-21/h5-15H,16H2,1-4H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	37
Syntrix Biosystems, Inc. US Patent					Assay Description An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...				US Patent US8981106 (2015) BindingDB Entry DOI: 10.7270/Q2WW7GC1
					More data for this Ligand-Target Pair