BDBM150905 US8981106, 94

SMILES: Fc1ccc(NC(=O)c2ccc(SCC(=O)c3ccc(Cl)c(c3)N(=O)=O)nc2)cc1

InChI Key: InChIKey=SXJMALNYPZWMFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM150905 (US8981106, 94) Show SMILES Fc1ccc(NC(=O)c2ccc(SCC(=O)c3ccc(Cl)c(c3)N(=O)=O)nc2)cc1 Show InChI InChI=1S/C20H13ClFN3O4S/c21-16-7-1-12(9-17(16)25(28)29)18(26)11-30-19-8-2-13(10-23-19)20(27)24-15-5-3-14(22)4-6-15/h1-10H,11H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	37
Syntrix Biosystems, Inc. US Patent					Assay Description An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...				US Patent US8981106 (2015) BindingDB Entry DOI: 10.7270/Q2WW7GC1
					More data for this Ligand-Target Pair