BDBM150949 US8981106, 138

SMILES: [O-]C(=O)c1cc(on1)C(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=FCMXVOTUPTZEMF-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 150949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM150949 (US8981106, 138) Show SMILES [O-]C(=O)c1cc(on1)C(=O)CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C18H12FN3O5S/c19-11-2-4-12(5-3-11)21-17(24)10-1-6-16(20-8-10)28-9-14(23)15-7-13(18(25)26)22-27-15/h1-8H,9H2,(H,21,24)(H,25,26)/p-1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	37
Syntrix Biosystems, Inc. US Patent					Assay Description An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...				US Patent US8981106 (2015) BindingDB Entry DOI: 10.7270/Q2WW7GC1
					More data for this Ligand-Target Pair