new BindingDB logo
myBDB logout

BDBM151255 US8987314, B51

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)[N+]#[C-]

InChI Key: InChIKey=GULLXKABLGIFDG-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151255   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151255
PNG
(US8987314, B51)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)[N+]#[C-]
Show InChI InChI=1/C19H18N4O5S3/c1-21-14-5-3-4-12(10-14)13-6-7-15-16(11-13)29-19(23-15)17(30(2,25)26)18(24)22-8-9-31(20,27)28/h3-7,10-11,17H,8-9H2,2H3,(H,22,24)(H2,20,27,28)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a<10n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


Citation and Details
More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151255
PNG
(US8987314, B51)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)[N+]#[C-]
Show InChI InChI=1/C19H18N4O5S3/c1-21-14-5-3-4-12(10-14)13-6-7-15-16(11-13)29-19(23-15)17(30(2,25)26)18(24)22-8-9-31(20,27)28/h3-7,10-11,17H,8-9H2,2H3,(H,22,24)(H2,20,27,28)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a<10n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


Citation and Details
More data for this
Ligand-Target Pair