BDBM151266 US8987314, B62

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1

InChI Key: InChIKey=XDYYGEHARABTCA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151266 (US8987314, B62) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1 Show InChI InChI=1S/C22H26N4O5S3/c1-33(28,29)20(21(27)24-9-12-34(23,30)31)22-25-18-8-7-16(14-19(18)32-22)15-5-4-6-17(13-15)26-10-2-3-11-26/h4-8,13-14,20H,2-3,9-12H2,1H3,(H,24,27)(H2,23,30,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151266 (US8987314, B62) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1 Show InChI InChI=1S/C22H26N4O5S3/c1-33(28,29)20(21(27)24-9-12-34(23,30)31)22-25-18-8-7-16(14-19(18)32-22)15-5-4-6-17(13-15)26-10-2-3-11-26/h4-8,13-14,20H,2-3,9-12H2,1H3,(H,24,27)(H2,23,30,31)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair