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BDBM151266 US8987314, B62

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1

InChI Key: InChIKey=XDYYGEHARABTCA-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151266   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151266
PNG
(US8987314, B62)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1
Show InChI InChI=1/C22H26N4O5S3/c1-33(28,29)20(21(27)24-9-12-34(23,30)31)22-25-18-8-7-16(14-19(18)32-22)15-5-4-6-17(13-15)26-10-2-3-11-26/h4-8,13-14,20H,2-3,9-12H2,1H3,(H,24,27)(H2,23,30,31)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


Citation and Details
More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Homo sapiens (Human))
BDBM151266
PNG
(US8987314, B62)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cccc(c1)N1CCCC1
Show InChI InChI=1/C22H26N4O5S3/c1-33(28,29)20(21(27)24-9-12-34(23,30)31)22-25-18-8-7-16(14-19(18)32-22)15-5-4-6-17(13-15)26-10-2-3-11-26/h4-8,13-14,20H,2-3,9-12H2,1H3,(H,24,27)(H2,23,30,31)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.20n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


Citation and Details
More data for this
Ligand-Target Pair