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SMILES: N[C@H](COc1cncc(c1)-c1ccc2cnccc2c1)Cc1ccccc1

InChI Key: InChIKey=VQMJTIJDQMAPOX-QFIPXVFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]


(Homo sapiens (Human))		BDBM15127
PNG
(5-isoquinolinyl pyridine 10f | 6-{5-[(2S)-2-amino-...)
Show SMILES N[C@H](COc1cncc(c1)-c1ccc2cnccc2c1)Cc1ccccc1 |r|
Show InChI InChI=1S/C23H21N3O/c24-22(10-17-4-2-1-3-5-17)16-27-23-12-21(14-26-15-23)18-6-7-20-13-25-9-8-19(20)11-18/h1-9,11-15,22H,10,16,24H2/t22-/m0/s1
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Article
PubMed
 89.6 -9.51n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem Lett 16: 3740-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.046
BindingDB Entry DOI: 10.7270/Q2ZP44C9
More data for this
Ligand-Target Pair