null

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cnn(Cc2ccccc2)c1

InChI Key: InChIKey=DPTYDKWVJVTOMJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151272 (US8987314, B68) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C22H23N5O5S3/c1-34(29,30)20(21(28)24-9-10-35(23,31)32)22-26-18-8-7-16(11-19(18)33-22)17-12-25-27(14-17)13-15-5-3-2-4-6-15/h2-8,11-12,14,20H,9-10,13H2,1H3,(H,24,28)(H2,23,31,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151272 (US8987314, B68) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C22H23N5O5S3/c1-34(29,30)20(21(28)24-9-10-35(23,31)32)22-26-18-8-7-16(11-19(18)33-22)17-12-25-27(14-17)13-15-5-3-2-4-6-15/h2-8,11-12,14,20H,9-10,13H2,1H3,(H,24,28)(H2,23,31,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair