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BDBM151283 US8987314, B79

SMILES: COc1cccc(c1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O

InChI Key: InChIKey=JUAJVOHSACYHSN-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151283   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151283
PNG
(US8987314, B79)
Show SMILES COc1cccc(c1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C19H21N3O6S3/c1-28-14-5-3-4-12(10-14)13-6-7-15-16(11-13)29-19(22-15)17(30(2,24)25)18(23)21-8-9-31(20,26)27/h3-7,10-11,17H,8-9H2,1-2H3,(H,21,23)(H2,20,26,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM151283
PNG
(US8987314, B79)
Show SMILES COc1cccc(c1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O
Show InChI InChI=1/C19H21N3O6S3/c1-28-14-5-3-4-12(10-14)13-6-7-15-16(11-13)29-19(22-15)17(30(2,24)25)18(23)21-8-9-31(20,26)27/h3-7,10-11,17H,8-9H2,1-2H3,(H,21,23)(H2,20,26,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)

More data for this
Ligand-Target Pair