null

SMILES: Cc1nnc(CNC(=O)C(c2nc3cc(C)c(cc3s2)-c2ccc(F)nc2)S(C)(=O)=O)o1

InChI Key: InChIKey=ASLAXURXJMELOP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151284 (US8987314, B80) Show SMILES Cc1nnc(CNC(=O)C(c2nc3cc(C)c(cc3s2)-c2ccc(F)nc2)S(C)(=O)=O)o1 Show InChI InChI=1S/C20H18FN5O4S2/c1-10-6-14-15(7-13(10)12-4-5-16(21)22-8-12)31-20(24-14)18(32(3,28)29)19(27)23-9-17-26-25-11(2)30-17/h4-8,18H,9H2,1-3H3,(H,23,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151284 (US8987314, B80) Show SMILES Cc1nnc(CNC(=O)C(c2nc3cc(C)c(cc3s2)-c2ccc(F)nc2)S(C)(=O)=O)o1 Show InChI InChI=1S/C20H18FN5O4S2/c1-10-6-14-15(7-13(10)12-4-5-16(21)22-8-12)31-20(24-14)18(32(3,28)29)19(27)23-9-17-26-25-11(2)30-17/h4-8,18H,9H2,1-3H3,(H,23,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair