BDBM151317 US8987314, B115

SMILES: COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1cccc(c1)C#N

InChI Key: InChIKey=DDWDJPVUGOSOSC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151317 (US8987314, B115) Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1cccc(c1)C#N Show InChI InChI=1S/C29H29N5O7S3/c1-41-13-11-32-27(35)22-7-5-21(6-8-22)23-9-10-24-25(16-23)42-29(34-24)26(28(36)33-12-14-44(31,39)40)43(37,38)18-20-4-2-3-19(15-20)17-30/h2-10,15-16,26H,11-14,18H2,1H3,(H,32,35)(H,33,36)(H2,31,39,40)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	107	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151317 (US8987314, B115) Show SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1cccc(c1)C#N Show InChI InChI=1S/C29H29N5O7S3/c1-41-13-11-32-27(35)22-7-5-21(6-8-22)23-9-10-24-25(16-23)42-29(34-24)26(28(36)33-12-14-44(31,39)40)43(37,38)18-20-4-2-3-19(15-20)17-30/h2-10,15-16,26H,11-14,18H2,1H3,(H,32,35)(H,33,36)(H2,31,39,40)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair