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BDBM151412 US8987314, B223

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)-c1nnc(N)s1

InChI Key: InChIKey=WCCMLCREEFHDAZ-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151412   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151412
PNG
(US8987314, B223)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)-c1nnc(N)s1
Show InChI InChI=1/C20H20N6O5S4/c1-34(28,29)16(17(27)23-8-9-35(22,30)31)19-24-14-7-6-13(10-15(14)32-19)11-2-4-12(5-3-11)18-25-26-20(21)33-18/h2-7,10,16H,8-9H2,1H3,(H2,21,26)(H,23,27)(H2,22,30,31)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.70n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM151412
PNG
(US8987314, B223)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(cc2s1)-c1ccc(cc1)-c1nnc(N)s1
Show InChI InChI=1/C20H20N6O5S4/c1-34(28,29)16(17(27)23-8-9-35(22,30)31)19-24-14-7-6-13(10-15(14)32-19)11-2-4-12(5-3-11)18-25-26-20(21)33-18/h2-7,10,16H,8-9H2,1H3,(H2,21,26)(H,23,27)(H2,22,30,31)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair