null

SMILES: NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(Cl)c1)S(=O)(=O)Cc1ccc(F)cc1

InChI Key: InChIKey=LVFCRDAUAVMDSQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151432 (US8987314, B243) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(Cl)c1)S(=O)(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C24H21ClFN3O5S3/c25-18-3-1-2-16(12-18)17-6-9-20-21(13-17)35-24(29-20)22(23(30)28-10-11-37(27,33)34)36(31,32)14-15-4-7-19(26)8-5-15/h1-9,12-13,22H,10-11,14H2,(H,28,30)(H2,27,33,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151432 (US8987314, B243) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1cccc(Cl)c1)S(=O)(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C24H21ClFN3O5S3/c25-18-3-1-2-16(12-18)17-6-9-20-21(13-17)35-24(29-20)22(23(30)28-10-11-37(27,33)34)36(31,32)14-15-4-7-19(26)8-5-15/h1-9,12-13,22H,10-11,14H2,(H,28,30)(H2,27,33,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair