BDBM151441 US8987314, B252

SMILES: CC(C)c1cc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)on1

InChI Key: InChIKey=ZGAMSRPMXFFEFE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151441 (US8987314, B252) Show SMILES CC(C)c1cc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)on1 Show InChI InChI=1S/C23H23N3O4S2/c1-14(2)19-12-17(30-26-19)13-24-22(27)21(32(3,28)29)23-25-18-10-9-16(11-20(18)31-23)15-7-5-4-6-8-15/h4-12,14,21H,13H2,1-3H3,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151441 (US8987314, B252) Show SMILES CC(C)c1cc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)on1 Show InChI InChI=1S/C23H23N3O4S2/c1-14(2)19-12-17(30-26-19)13-24-22(27)21(32(3,28)29)23-25-18-10-9-16(11-20(18)31-23)15-7-5-4-6-8-15/h4-12,14,21H,13H2,1-3H3,(H,24,27)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair