null

SMILES: Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)OC(C)(C)C)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O

InChI Key: InChIKey=YWCHTNSPNIFYNH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151463 (US8987314, B274) Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)OC(C)(C)C)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O Show InChI InChI=1S/C24H29N3O7S3/c1-14-12-18-19(13-17(14)15-6-8-16(9-7-15)23(29)34-24(2,3)4)35-22(27-18)20(36(5,30)31)21(28)26-10-11-37(25,32)33/h6-9,12-13,20H,10-11H2,1-5H3,(H,26,28)(H2,25,32,33)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151463 (US8987314, B274) Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(=O)OC(C)(C)C)C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O Show InChI InChI=1S/C24H29N3O7S3/c1-14-12-18-19(13-17(14)15-6-8-16(9-7-15)23(29)34-24(2,3)4)35-22(27-18)20(36(5,30)31)21(28)26-10-11-37(25,32)33/h6-9,12-13,20H,10-11H2,1-5H3,(H,26,28)(H2,25,32,33)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair