BDBM151465 US8987314, B276

SMILES: CC(C)(C)OC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=TZQNYSMYELNAHD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151465 (US8987314, B276) Show SMILES CC(C)(C)OC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C29H31N3O7S3/c1-29(2,3)39-28(34)21-11-9-20(10-12-21)22-13-14-23-24(17-22)40-27(32-23)25(26(33)31-15-16-42(30,37)38)41(35,36)18-19-7-5-4-6-8-19/h4-14,17,25H,15-16,18H2,1-3H3,(H,31,33)(H2,30,37,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151465 (US8987314, B276) Show SMILES CC(C)(C)OC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C29H31N3O7S3/c1-29(2,3)39-28(34)21-11-9-20(10-12-21)22-13-14-23-24(17-22)40-27(32-23)25(26(33)31-15-16-42(30,37)38)41(35,36)18-19-7-5-4-6-8-19/h4-14,17,25H,15-16,18H2,1-3H3,(H,31,33)(H2,30,37,38)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair