null

SMILES: Cc1nnc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccc(cc2)C(=O)OC(C)(C)C)S(C)(=O)=O)s1

InChI Key: InChIKey=SYAPLKNCGPHOGB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151468 (US8987314, B279) Show SMILES Cc1nnc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccc(cc2)C(=O)OC(C)(C)C)S(C)(=O)=O)s1 Show InChI InChI=1S/C25H26N4O5S3/c1-14-28-29-20(35-14)13-26-22(30)21(37(5,32)33)23-27-18-11-10-17(12-19(18)36-23)15-6-8-16(9-7-15)24(31)34-25(2,3)4/h6-12,21H,13H2,1-5H3,(H,26,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151468 (US8987314, B279) Show SMILES Cc1nnc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccc(cc2)C(=O)OC(C)(C)C)S(C)(=O)=O)s1 Show InChI InChI=1S/C25H26N4O5S3/c1-14-28-29-20(35-14)13-26-22(30)21(37(5,32)33)23-27-18-11-10-17(12-19(18)36-23)15-6-8-16(9-7-15)24(31)34-25(2,3)4/h6-12,21H,13H2,1-5H3,(H,26,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.6	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair