BDBM151477 US8987314, B288

SMILES: COCCN(C)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=ZYNFAQNJIWQTKK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151477 (US8987314, B288) Show SMILES COCCN(C)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C30H31F3N4O7S3/c1-37(14-15-44-2)29(39)21-7-5-20(6-8-21)22-9-12-24-25(17-22)45-28(36-24)26(27(38)35-13-16-47(34,42)43)46(40,41)18-19-3-10-23(11-4-19)30(31,32)33/h3-12,17,26H,13-16,18H2,1-2H3,(H,35,38)(H2,34,42,43)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151477 (US8987314, B288) Show SMILES COCCN(C)C(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C30H31F3N4O7S3/c1-37(14-15-44-2)29(39)21-7-5-20(6-8-21)22-9-12-24-25(17-22)45-28(36-24)26(27(38)35-13-16-47(34,42)43)46(40,41)18-19-3-10-23(11-4-19)30(31,32)33/h3-12,17,26H,13-16,18H2,1-2H3,(H,35,38)(H2,34,42,43)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair