BDBM151510 US8987314, B321

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(cc1)C(=O)N1CC(F)(F)C1

InChI Key: InChIKey=QIKBWOHCJNOJSN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic Lipase (HL) (Homo sapiens (Human))	BDBM151510 (US8987314, B321) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(cc1)C(=O)N1CC(F)(F)C1 Show InChI InChI=1S/C22H22F2N4O6S3/c1-36(31,32)18(19(29)26-8-9-37(25,33)34)20-27-16-10-15(6-7-17(16)35-20)13-2-4-14(5-3-13)21(30)28-11-22(23,24)12-28/h2-7,10,18H,8-9,11-12H2,1H3,(H,26,29)(H2,25,33,34)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	175	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151510 (US8987314, B321) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(cc1)C(=O)N1CC(F)(F)C1 Show InChI InChI=1S/C22H22F2N4O6S3/c1-36(31,32)18(19(29)26-8-9-37(25,33)34)20-27-16-10-15(6-7-17(16)35-20)13-2-4-14(5-3-13)21(30)28-11-22(23,24)12-28/h2-7,10,18H,8-9,11-12H2,1H3,(H,26,29)(H2,25,33,34)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair