null

SMILES: NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccccc1F)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=NPEYYOPSDDQKKS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM151554 (US8987314, B365) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccccc1F)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H21F4N3O6S3/c26-19-4-2-1-3-18(19)16-7-10-20-21(13-16)39-24(32-20)22(23(33)31-11-12-41(30,36)37)40(34,35)14-15-5-8-17(9-6-15)38-25(27,28)29/h1-10,13,22H,11-12,14H2,(H,31,33)(H2,30,36,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM151554 (US8987314, B365) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccccc1F)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C25H21F4N3O6S3/c26-19-4-2-1-3-18(19)16-7-10-20-21(13-16)39-24(32-20)22(23(33)31-11-12-41(30,36)37)40(34,35)14-15-5-8-17(9-6-15)38-25(27,28)29/h1-10,13,22H,11-12,14H2,(H,31,33)(H2,30,36,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
					More data for this Ligand-Target Pair