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BDBM151563 US8987314, B374

SMILES: CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ncccn1

InChI Key: InChIKey=WNCXMLGCHIHIJB-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151563   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151563
PNG
(US8987314, B374)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ncccn1
Show InChI InChI=1/C16H17N5O5S3/c1-28(23,24)13(15(22)20-7-8-29(17,25)26)16-21-11-9-10(3-4-12(11)27-16)14-18-5-2-6-19-14/h2-6,9,13H,7-8H2,1H3,(H,20,22)(H2,17,25,26)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23.7n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM151563
PNG
(US8987314, B374)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ncccn1
Show InChI InChI=1/C16H17N5O5S3/c1-28(23,24)13(15(22)20-7-8-29(17,25)26)16-21-11-9-10(3-4-12(11)27-16)14-18-5-2-6-19-14/h2-6,9,13H,7-8H2,1H3,(H,20,22)(H2,17,25,26)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.800n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair