BDBM152494 (E)-2-(2,4-dichlorophenyl)-N'-(2-oxo-1-propylindolin-3-ylidene)acetohydrazide (2)

SMILES: CCCN1C(=O)\C(=N\NC(=O)Cc2ccc(Cl)cc2Cl)c2ccccc12

InChI Key: InChIKey=XIPBEEJSVKYMSR-PTGBLXJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae)	BDBM152494 ((E)-2-(2,4-dichlorophenyl)-N'-(2-oxo-1-propyli...) Show SMILES CCCN1C(=O)\C(=N\NC(=O)Cc2ccc(Cl)cc2Cl)c2ccccc12 Show InChI InChI=1S/C19H17Cl2N3O2/c1-2-9-24-16-6-4-3-5-14(16)18(19(24)26)23-22-17(25)10-12-7-8-13(20)11-15(12)21/h3-8,11H,2,9-10H2,1H3,(H,22,25)/b23-18+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hazara University					Assay Description 10 µL of test samples (5 mg/mL DMSO solution) were reconstituted in 100 µL of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...				Bioorg Chem 60: 42-8 (2015) Article DOI: 10.1016/j.bioorg.2015.03.005 BindingDB Entry DOI: 10.7270/Q2DR2T7R
					More data for this Ligand-Target Pair