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BDBM152497 (E)-N'-(6-Bromo-2-oxoindolin-3-ylidene)-2-(2,4-dichlorophenyl)acetohydrazide (12)

SMILES: Clc1ccc(CC(=O)N\N=C2\C(=O)Nc3cc(Br)ccc23)c(Cl)c1

InChI Key: InChIKey=ARTIQGMBCWGCEJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152497   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-glucosidase MAL12


(Saccharomyces cerevisiae)
BDBM152497
PNG
((E)-N'-(6-Bromo-2-oxoindolin-3-ylidene)-2-(2,4...)
Show SMILES Clc1ccc(CC(=O)N\N=C2\C(=O)Nc3cc(Br)ccc23)c(Cl)c1
Show InChI InChI=1S/C16H10BrCl2N3O2/c17-9-2-4-11-13(6-9)20-16(24)15(11)22-21-14(23)5-8-1-3-10(18)7-12(8)19/h1-4,6-7H,5H2,(H,21,23)(H,20,22,24)
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Hazara University



Assay Description
10 ÁL of test samples (5 mg/mL DMSO solution) were reconstituted in 100 ÁL of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...


Bioorg Chem 60: 42-8 (2015)


Article DOI: 10.1016/j.bioorg.2015.03.005
BindingDB Entry DOI: 10.7270/Q2DR2T7R
More data for this
Ligand-Target Pair