BDBM152505 (2,4-dimethoxyphenyl)(4-methoxyphenyl)methanone (18)
SMILES: COc1ccc(cc1)C(=O)c1ccc(OC)cc1OC
InChI Key: InChIKey=VFTDVICZBGDMMB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Acetylcholinesterase (Homo sapiens (Human)) | BDBM152505 ((2,4-dimethoxyphenyl)(4-methoxyphenyl)methanone (1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 5.88 | n/a | 5.25 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 µL of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair |