BDBM152507 (2-bromo-4-hydroxyphenyl)(3,4-dihydroxyphenyl)methanone (20)
SMILES: Oc1ccc(C(=O)c2ccc(O)c(O)c2)c(Br)c1
InChI Key: InChIKey=UAWWXQLOFBKULI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Acetylcholinesterase (Homo sapiens (Human)) | BDBM152507 ((2-bromo-4-hydroxyphenyl)(3,4-dihydroxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.06 | n/a | 4.71 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 µL of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair |