BDBM152586 D-Saccharic acid 1,4 lactone::D-Saccharic acid 1,4-lactone::D-Saccharic acid 1,4-lactone ::D-saccharic acid-1,4-lactone

SMILES: OC(C1OC(=O)C(O)C1O)C(O)=O

InChI Key: InChIKey=XECPAIJNBXCOBO-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 152586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-glucuronidase (β-glucuronidase) (Bos taurus (Bovine))	BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) Show SMILES OC(C1OC(=O)C(O)C1O)C(O)=O Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA (UiTM)					Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...				Bioorg Chem 61: 36-44 (2015) Article DOI: 10.1016/j.bioorg.2015.05.010 BindingDB Entry DOI: 10.7270/Q2HH6HTP
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Beta-glucuronidase (β-glucuronidase) (Bos taurus (Bovine))	BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) Show SMILES OC(C1OC(=O)C(O)C1O)C(O)=O Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL...				Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP
					More data for this Ligand-Target Pair
Beta-glucuronidase (EcGUS) (Escherichia coli (Enterobacteria))	BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) Show SMILES OC(C1OC(=O)C(O)C1O)C(O)=O Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.84E+4	n/a	n/a	n/a	n/a	7.0	37
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was evaluated by a biochemical assay, based on the measurement of the absorbance of p-nitrophenol at 405 nm,...				J Enzyme Inhib Med Chem 27: 348-55 (2012) Article DOI: 10.3109/14756366.2011.590804 BindingDB Entry DOI: 10.7270/Q2N29VV5
					More data for this Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) Show SMILES OC(C1OC(=O)C(O)C1O)C(O)=O Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars		n/a	n/a	4.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...				Bioorg Chem 72: 323-332 (2017) BindingDB Entry DOI: 10.7270/Q28051GP
					More data for this Ligand-Target Pair
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human))	BDBM152586 (D-Saccharic acid 1,4 lactone | D-Saccharic acid 1,...) Show SMILES OC(C1OC(=O)C(O)C1O)C(O)=O Show InChI InChI=1S/C6H8O7/c7-1-2(8)6(12)13-4(1)3(9)5(10)11/h1-4,7-9H,(H,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...				Bioorg Chem 68: 56-63 (2016) Article DOI: 10.1016/j.bioorg.2016.07.008 BindingDB Entry DOI: 10.7270/Q2RV0MGS
					More data for this Ligand-Target Pair