BDBM152696 PSR-3-283A
SMILES: [H][C@@]12[C@H](CO)C(=O)N1[C@@H](C([O-])=O)C(C)(C)S2(=O)=O
InChI Key: InChIKey=ODGTYAIFNCCEHW-JCGDXUMPSA-M
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SHV-1 beta-lactamase (Klebsiella pneumoniae (Enterobacteria)) | BDBM152696 (PSR-3-283A) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 560 | n/a | 320 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Case Western Reserve University | Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t... | Biochemistry 54: 734-43 (2015) Article DOI: 10.1021/bi501197t BindingDB Entry DOI: 10.7270/Q2736PNW | |||||||||||
More data for this Ligand-Target Pair |