BDBM152699 (S)-2-Amino-5-propionimidamidopentanoic acid (8)::hDDAH inhibitor, 1d

SMILES: CCC(=N)NCCC[C@H](N)C(O)=O

InChI Key: InChIKey=ZYIBCZWVLDODOL-LURJTMIESA-N

Data: 2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM152699 ((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...) Show SMILES CCC(=N)NCCC[C@H](N)C(O)=O |r| Show InChI InChI=1S/C8H17N3O2/c1-2-7(10)11-5-3-4-6(9)8(12)13/h6H,2-5,9H2,1H3,(H2,10,11)(H,12,13)/t6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	7.25E+3	n/a	1.61E+4	n/a	n/a	n/a	n/a	7.4	n/a
Northwestern University					Assay Description The assay mixture contained L-arginine (10 μM), NADPH (100 μM), oxyhemoglobin (0.125 mg/mL), tetrahydrobiopterin (10 μM), and differen...				Biochemistry 54: 2530-8 (2015) Article DOI: 10.1021/acs.biochem.5b00135 BindingDB Entry DOI: 10.7270/Q23B5XWQ
					More data for this Ligand-Target Pair
Dimethylarginine dimethylaminohydrolase 1 (DDAH) (Homo sapiens (Human))	BDBM152699 ((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...) Show SMILES CCC(=N)NCCC[C@H](N)C(O)=O |r| Show InChI InChI=1S/C8H17N3O2/c1-2-7(10)11-5-3-4-6(9)8(12)13/h6H,2-5,9H2,1H3,(H2,10,11)(H,12,13)/t6-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.45E+5	-5.44	n/a	n/a	n/a	n/a	n/a	7.4	37
Christian-Albrechts-University					Assay Description A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...				J Enzyme Inhib Med Chem 27: 24-8 (2012) Article DOI: 10.3109/14756366.2011.573480 BindingDB Entry DOI: 10.7270/Q24B3064
					More data for this Ligand-Target Pair				3D Structure (crystal)