BDBM152724 2477
SMILES: O=C(NCC#N)OCc1ccccc1
InChI Key: InChIKey=DVUXKEFDAGQPQU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cysteine protease SpeB (SpeB) (Streptococcus pyogenes (Firmicutes)) | BDBM152724 (2477) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | 8.00E+3 | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
The Scripps Research Institute | Assay Description SpeB was incubated at 50 nM in the presence of increasing amounts of inhibitor (3 μM to 200 μM) in a reaction buffer consisting of PBS at p... | Biochemistry 54: 4365-73 (2015) Article DOI: 10.1021/acs.biochem.5b00607 BindingDB Entry DOI: 10.7270/Q2KD1WNP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Papain (Carica papaya) | BDBM152724 (2477) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | 4.50E+4 | n/a | 7.70E+4 | n/a | n/a | n/a | n/a | 7.4 | n/a |
The Scripps Research Institute | Assay Description SpeB was incubated at 50 nM in the presence of increasing amounts of inhibitor (3 μM to 200 μM) in a reaction buffer consisting of PBS at p... | Biochemistry 54: 4365-73 (2015) Article DOI: 10.1021/acs.biochem.5b00607 BindingDB Entry DOI: 10.7270/Q2KD1WNP | |||||||||||
More data for this Ligand-Target Pair |